4.6 Article

Double-mode detection of HClO by naked eye and concurrent fluorescence increasing in absolute PBS

Journal

RSC ADVANCES
Volume 6, Issue 42, Pages 35315-35317

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra03959f

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Funding

  1. Scientific Research Foundation of Northwest AF University [Z111021103, Z111021107]
  2. National Natural Science Foundation of China [21472016, 21272030, 21476185]
  3. State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University [2013005]

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A water soluble fluorescent probe WCN was successfully designed and synthesized based on acenaphthenequinone. It can be employed for double-mode detection of HClO by the naked eye and concurrent significant fluorescence increasing in absolute PBS. The detection limit was measured down to 77 pM. Especially important, WCN works well in both living cells and a living mouse.

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