Journal
RSC ADVANCES
Volume 6, Issue 52, Pages 47134-47137Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra05151k
Keywords
-
Categories
Funding
- FAPESP [2014/05653-5]
- CNPq
- CAPES
Ask authors/readers for more resources
Direct detection of dopamine (DA) in serum samples without any type of extraction or pre-treatment has been a great challenge for biomedical analysis. This paper reports the development of a sensor consisting of polymer brushes reinforced with multi-walled carbon nanotubes, that was used to determine levels of dopamine in human blood serum. The structure and morphology of the as-prepared hybrid nanomaterials were characterized and confirmed by scanning electron microscopy and electrochemistry techniques. This methodology employs differential pulse voltammetry to detect dopamine in human serum samples at concentrations ranging from 0.1 mu M to 10 mu M with an obtained detection limit of 40.5 nmol L-1 (R = 0.996). This sensor provides an inexpensive and easy-to-use device with high degrees of sensitivity and selectivity for monitoring DA in human blood serum samples.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available