4.3 Article

OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research

Journal

ONCOTARGET
Volume 7, Issue 35, Pages 56147-56152

Publisher

IMPACT JOURNALS LLC
DOI: 10.18632/oncotarget.11269

Keywords

web-service; statistics; survival; maximum lifespan; healthspan; Gerotarget

Funding

  1. National Research Foundation of Korea [2015R1A2A2A01004921]
  2. Korea Institute of Oriental Medicine grant [K15809]
  3. Korean Health Technology RD Project [HI11C1609]
  4. National Research Foundation of Korea [2015R1A2A2A01004921] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Online application for survival analysis (OASIS) has served as a popular and convenient platform for the statistical analysis of various survival data, particularly in the field of aging research. With the recent advances in the fields of aging research that deal with complex survival data, we noticed a need for updates to the current version of OASIS. Here, we report OASIS 2 (http://sbi.postech.ac.kr/oasis2), which provides extended statistical tools for survival data and an enhanced user interface. In particular, OASIS 2 enables the statistical comparison of maximal lifespans, which is potentially useful for determining key factors that limit the lifespan of a population. Furthermore, OASIS 2 provides statistical and graphical tools that compare values in different conditions and times. That feature is useful for comparing age-associated changes in physiological activities, which can be used as indicators of healthspan. We believe that OASIS 2 will serve as a standard platform for survival analysis with advanced and user-friendly statistical tools for experimental biologists in the field of aging research.

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