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Suppressive Effects of Tea Catechins on Breast Cancer

Journal

NUTRIENTS
Volume 8, Issue 8, Pages -

Publisher

MDPI
DOI: 10.3390/nu8080458

Keywords

Camellia sinensis; anticancer; antioxidant; signaling pathway; anti-proliferation; DNA methylation; metastasis

Funding

  1. Specialized Research Fund for the Doctoral Program of Higher Education of China (SRFDP) [20110101110094]

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Tea leaf (Camellia sinensis) is rich in catechins, which endow tea with various health benefits. There are more than ten catechin compounds in tea, among which epigallocatechingallate (EGCG) is the most abundant. Epidemiological studies on the association between tea consumption and the risk of breast cancer were summarized, and the inhibitory effects of tea catechins on breast cancer, with EGCG as a representative compound, were reviewed in the present paper. The controversial results regarding the role of tea in breast cancer and areas for further study were discussed.

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