Journal
BIOMEDICAL OPTICS EXPRESS
Volume 8, Issue 1, Pages 177-192Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.8.000177
Keywords
-
Funding
- German Federal Ministry of Economics and Energy (BMWi) within the Promotion of Joint Industrial Research Programme (IGF)
- Association for Research in Precision Mechanics, Optics and Medical Technology (F.O.M.) under German Federation of Industrial Research Associations (AiF) [18129N]
- German Research Foundation through the Cluster of Excellence REBIRTH [DFG EXC62/3]
- DFG [ZW 64/4-1]
- German Ministry for Education and Science (BMBF) [13N12606]
- ministry of Lower Saxony
- Volkswagen Stiftung [BIOFABRICATION FOR NIFE: VWZN2860]
Ask authors/readers for more resources
Can photothermal gold nanoparticle mediated laser manipulation be applied to induce cardiac contraction? Based on our previous work, we present a novel concept of cell stimulation. A 532 nm picosecond laser was employed to heat gold nanoparticles on cardiomyocytes. This leads to calcium oscillations in the HL-1 cardiomyocyte cell line. As calcium is connected to the contractility, we aimed to alter the contraction rate of native and stem cell derived cardiomyocytes. A contraction rate increase was particularly observed in calcium containing buffer with neonatal rat cardiomyocytes. Consequently, the study provides conceptual ideas for a light based, nanoparticle mediated stimulation system. (C) 2016 Optical Society of America
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
