Journal
BIOMEDICAL OPTICS EXPRESS
Volume 7, Issue 11, Pages 4605-4619Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.7.004605
Keywords
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Funding
- Nano-Tera project ObeSense
- Nano-Tera project ParaTex
- Nano-Tera project NewbornCare
- Clinical Research Priority Program, Tumor Oxygenation, of the University of Zurich
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Change of muscle tissue oxygen saturation (StO(2)), due to exercise, measured by near infrared spectroscopy (NIRS) is known to be lower for subjects with higher adipose tissue thickness. This is most likely not physiological but caused by the superficial fat and adipose tissue. In this paper we assessed, in vitro, the influence of adipose tissue thickness on muscle StO(2), measured by NIRS oximeters. We measured StO(2) of a liquid phantom by 3 continuous wave (CW) oximeters (Sensmart Model X-100 Universal Oximetry System, INVOS 5100C, and OxyPrem v1.3), as well as a frequency-domain oximeter, OxiplexTS, through superficial layers with 4 different thicknesses. Later, we employed the results to calibrate OxyPrem v1.3 for adipose tissue thickness in-vivo. (C) 2016 Optical Society of America
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