Journal
ACS CATALYSIS
Volume 6, Issue 7, Pages 4710-4714Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.6b01045
Keywords
hydrogenation; alkynes; ruthenium catalysis; deuterium labeling; trans-alkenes; continuous flow
Categories
Funding
- Danish National Research Foundation [DNRF118]
- Villum Foundation
- Programme Commission on Strategic Growth Technologies
- Innovation Fund Denmark [0603-00439B]
- H. Lundbeck A/S
- Danish Council for Independent Research: Technology and Production Sciences
- Carlsberg Foundation
- Lundbeck Foundation
- Aarhus University
Ask authors/readers for more resources
An efficient trans-selective hydrogenation of alkynes under low hydrogen pressure and low reaction temperatures is reported, applying a commercially available ruthenium hydride complex. The developed reaction conditions, which tolerate a variety of functional groups, are carried out in a two-chamber setup with ex situ generated hydrogen. The reaction setup is highly suitable for deuterium labeling. The trans-selective hydrogenation was extrapolated to a transfer hydrogenation protocol, employing a packed bed immobilized ruthenium hydride catalyst in continuous flow with a retention time of only 10 min.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available