Journal
ACS CATALYSIS
Volume 6, Issue 8, Pages 5236-5244Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.6b01102
Keywords
enantioselective synthesis; triple catalysis; iron catalysis; copper catalysis; organocatalysis; borrowing hydrogen
Categories
Funding
- Agence Nationale pour la Recherche [ANR-13-PDOC-0007-01]
- Centre National de la Recherche Scientifique (CNRS)
- Aix-Marseille Universite
- Agence Nationale de la Recherche (ANR) [ANR-13-PDOC-0007] Funding Source: Agence Nationale de la Recherche (ANR)
Ask authors/readers for more resources
A detailed study of the enantioselective borrowing hydrogen functionalization of allylic alcohols has allowed us to improve our understanding of the reaction parameters affecting both rate and enantiocontrol. This subsequently led to the identification of a triple catalysis combination of iron catalysts, copper catalysts, and organo-catalysts. By this cooperative action among three distinct activation modes, a wide variety of allylic alcohols have been functionalized in improved typical 90% ee, providing rapid access to crucial synthetic building blocks.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available