Related references
Note: Only part of the references are listed.Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
Sidi Chen et al.
CELL (2015)
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing
Shin-Heng Chiou et al.
GENES & DEVELOPMENT (2015)
Transflip mutations produce deletions in pancreatic cancer
Alexis L. Norris et al.
GENES CHROMOSOMES & CANCER (2015)
Sequential cancer mutations in cultured human intestinal stem cells
Jarno Drost et al.
NATURE (2015)
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
Silvana Konermann et al.
NATURE (2015)
Whole genomes redefine the mutational landscape of pancreatic cancer
Nicola Waddell et al.
NATURE (2015)
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer
Erica J. Childs et al.
NATURE GENETICS (2015)
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Pawel K. Mazur et al.
NATURE MEDICINE (2015)
Highly efficient Cas9-mediated transcriptional programming
Alejandro Chavez et al.
NATURE METHODS (2015)
CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice
Julia Weber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Marc Zuckermann et al.
NATURE COMMUNICATIONS (2015)
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer
Roland Rad et al.
NATURE GENETICS (2015)
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
Randall J. Platt et al.
CELL (2014)
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
Francisco J. Sanchez-Rivera et al.
NATURE (2014)
In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
Danilo Maddalo et al.
NATURE (2014)
CRISPR-mediated direct mutation of cancer genes in the mouse liver
Wen Xue et al.
NATURE (2014)
CRISPR-Cas systems for editing, regulating and targeting genomes
Jeffry D. Sander et al.
NATURE BIOTECHNOLOGY (2014)
Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing
Dirk Heck et al.
NATURE BIOTECHNOLOGY (2014)
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
Hao Yin et al.
NATURE BIOTECHNOLOGY (2014)
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
Brian M. Wolpin et al.
NATURE GENETICS (2014)
Simple and Rapid In Vivo Generation of Chromosomal Rearrangements using CRISPR/Cas9 Technology
Rafael B. Blasco et al.
CELL REPORTS (2014)
Genetically engineered mouse models of pancreatic adenocarcinoma
Carmen Guerra et al.
MOLECULAR ONCOLOGY (2013)
Cas9 as a versatile tool for engineering biology
Prashant Mali et al.
NATURE METHODS (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
End-joining, translocations and cancer
Samuel F. Bunting et al.
NATURE REVIEWS CANCER (2013)
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
Andrew V. Biankin et al.
NATURE (2012)
RNA-guided genetic silencing systems in bacteria and archaea
Blake Wiedenheft et al.
NATURE (2012)
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
Karen M. Mann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Inactivation of Brca2 Promotes Trp53-Associated but Inhibits KrasG12D-Dependent Pancreatic Cancer Development in Mice
Matthew Rowley et al.
GASTROENTEROLOGY (2011)
Validation of preclinical multiparametric imaging for prediction of necrosis in hepatocellular carcinoma after embolization
Rickmer Braren et al.
JOURNAL OF HEPATOLOGY (2011)
Aneuploidy Drives Genomic Instability in Yeast
Jason M. Sheltzer et al.
SCIENCE (2011)
Germline Brca2 Heterozygosity Promotes KrasG12D -Driven Carcinogenesis in a Murine Model of Familial Pancreatic Cancer
Ferdinandos Skoulidis et al.
CANCER CELL (2010)
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
Peter J. Campbell et al.
NATURE (2010)
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Josiane E. Garneau et al.
NATURE (2010)
CRISPR/Cas, the Immune System of Bacteria and Archaea
Philippe Horvath et al.
SCIENCE (2010)
Mitotic chromosomal instability and cancer: mouse modelling of the human disease
Juan-Manuel Schvartzman et al.
NATURE REVIEWS CANCER (2010)
VarScan: variant detection in massively parallel sequencing of individual and pooled samples
Daniel C. Koboldt et al.
BIOINFORMATICS (2009)
The Sequence Alignment/Map format and SAMtools
Heng Li et al.
BIOINFORMATICS (2009)
A Cre-IoXP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors
Barbara Seidler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
Bret R. Williams et al.
SCIENCE (2008)
A global double-fluorescent cre reporter mouse
Mandar Deepak Muzumdar et al.
GENESIS (2007)
Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina
Hassan Nakhai et al.
DEVELOPMENT (2007)
Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations
C. A. Griffin et al.
CYTOGENETIC AND GENOME RESEARCH (2007)
Pancreatic adenocarcinoma - Genetic portrait from chromosomes to microarrays
Ritva Karhu et al.
GENES CHROMOSOMES & CANCER (2006)
Electroporation as a method for high-level nonviral gene transfer to the lung
DA Dean et al.
GENE THERAPY (2003)
Electric gene transfer to the liver following systemic administration of plasmid DNA
F Liu et al.
GENE THERAPY (2002)
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson et al.
GENES & DEVELOPMENT (2001)
Karyotyping mouse chromosomes by multiplex-FISH (M-FISH)
I Jentsch et al.
CHROMOSOME RESEARCH (2001)