Related references
Note: Only part of the references are listed.Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
Cyril Ribeyre et al.
CELL REPORTS (2016)
Interplay between Ku and Replication Protein A in the Restriction of Exo1-mediated DNA Break End Resection
Danielle S. Krasner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair
Christine K. Schmidt et al.
NATURE CELL BIOLOGY (2015)
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice
Ismail Hassan Ismail et al.
NATURE CELL BIOLOGY (2015)
ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1
Amanda W. Kijas et al.
NUCLEIC ACIDS RESEARCH (2015)
PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
Takashi Ochi et al.
SCIENCE (2015)
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway
Mengtan Xing et al.
NATURE COMMUNICATIONS (2015)
Neddylation Promotes Ubiquitylation and Release of Ku from DNA-Damage Sites
Jessica S. Brown et al.
CELL REPORTS (2015)
DNA double strand break repair pathway choice: a chromatin based decision?
T. Clouaire et al.
NUCLEUS (2015)
DNA double strand break repair pathway choice: a chromatin based decision?
T. Clouaire et al.
NUCLEUS (2015)
ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor
Martin F. Lavin et al.
BIOMOLECULES (2015)
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1
Olivia Barton et al.
JOURNAL OF CELL BIOLOGY (2014)
DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
Atsushi Shibata et al.
MOLECULAR CELL (2014)
CtIP Maintains Stability at Common Fragile Sites and Inverted Repeats by End Resection-Independent Endonuclease Activity
Hailong Wang et al.
MOLECULAR CELL (2014)
Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection
Nodar Makharashvili et al.
MOLECULAR CELL (2014)
Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks
Elda Cannavo et al.
NATURE (2014)
Causes and consequences of replication stress
Michelle K. Zeman et al.
NATURE CELL BIOLOGY (2014)
DNA Dynamics during Early Double-Strand Break Processing Revealed by Non-Intrusive Imaging of Living Cells
Hicham Saad et al.
PLOS GENETICS (2014)
The complexity of DNA double strand breaks is a critical factor enhancing end-resection
Hirohiko Yajima et al.
DNA REPAIR (2013)
The SOSS1 single-stranded DNA binding complex promotes DNA end resection in concert with Exo1
Soo-Hyun Yang et al.
EMBO JOURNAL (2013)
DNA structure-specific priming of ATR activation by DNA-PKcs
Sophie Vidal-Eychenie et al.
JOURNAL OF CELL BIOLOGY (2013)
A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair
Sebastien Britton et al.
JOURNAL OF CELL BIOLOGY (2013)
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
Yosef Shiloh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase
Elizabeth M. Kass et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The Ku Heterodimer and the Metabolism of Single-Ended DNA Double-Strand Breaks
Alessia Balestrini et al.
CELL REPORTS (2013)
A high-throughput, flow cytometry-based method to quantify DN-End resection in mammalian cells
Josep V. Forment et al.
CYTOMETRY PART A (2012)
Human Ku70/80 Protein Blocks Exonuclease 1-mediated DNA Resection in the Presence of Human Mre11 or Mre11/Rad50 Protein Complex
Jingxin Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Loss of ATM kinase activity leads to embryonic lethality in mice
Jeremy A. Daniel et al.
JOURNAL OF CELL BIOLOGY (2012)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Topoisomerase I poisoning results in PARP-mediated replication fork reversal
Arnab Ray Chaudhuri et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
ATM Protein-dependent Phosphorylation of Rad50 Protein Regulates DNA Repair and Cell Cycle Control
Magtouf Gatei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Functional Interplay of the Mre11 Nuclease and Ku in the Response to Replication-Associated DNA Damage
Steven S. Foster et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1
Valerie Garcia et al.
NATURE (2011)
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
Verena Quennet et al.
NUCLEIC ACIDS RESEARCH (2011)
Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks
Qiao Cheng et al.
NUCLEIC ACIDS RESEARCH (2011)
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
Anand G. Patel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Release of Ku and MRN from DNA Ends by Mre11 Nuclease Activity and Ctp1 Is Required for Homologous Recombination Repair of Double-Strand Breaks
Petra Langerak et al.
PLOS GENETICS (2011)
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
Michael R. Lieber
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
Eleni P. Mimitou et al.
EMBO JOURNAL (2010)
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
Eun Yong Shim et al.
EMBO JOURNAL (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
Brandi L. Mahaney et al.
BIOCHEMICAL JOURNAL (2009)
Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
Pablo Huertas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
The emerging role of nuclear architecture in DNA repair and genome maintenance
Tom Misteli et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
Jeffrey Buis et al.
CELL (2008)
Ku80 removal from DNA through double strand break-induced ubiquitylation
Lisa Postow et al.
JOURNAL OF CELL BIOLOGY (2008)
CDK targets Sae2 to control DNA-end resection and homologous recombination
Pablo Huertas et al.
NATURE (2008)
A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex
Aude Dupre et al.
NATURE CHEMICAL BIOLOGY (2008)
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
Bettina M. Lengsfeld et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
A guided tour into subcellular colocalization analysis in light microscopy
S. Bolte et al.
JOURNAL OF MICROSCOPY (2006)
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
JJJ Leahy et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
I Hickson et al.
CANCER RESEARCH (2004)
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes
T Furuta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Studies on the mode of Ku interaction with DNA
D Arosio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
JR Walker et al.
NATURE (2001)
Ku entry into DNA inhibits inward DNA transactions in vitro
P Frit et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
S Li et al.
NATURE (2000)
Share Paper
