4.8 Article

Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

C2H2 zinc finger proteins greatly expand the human regulatory lexicon

Hamed S. Najafabadi et al.

NATURE BIOTECHNOLOGY (2015)

Article Biotechnology & Applied Microbiology

Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors

Xiaoling Wang et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

A systematic survey of the Cys2His2 zinc finger DNA-binding landscape

Anton V. Persikov et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biotechnology & Applied Microbiology

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai et al.

NATURE BIOTECHNOLOGY (2015)

Article Biotechnology & Applied Microbiology

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

Richard L. Frock et al.

NATURE BIOTECHNOLOGY (2015)

Article Biochemistry & Molecular Biology

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases

Seung Woo Cho et al.

GENOME RESEARCH (2014)

Article Biochemistry & Molecular Biology

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

Suresh Ramakrishna et al.

GENOME RESEARCH (2014)

Article Biochemistry & Molecular Biology

Simultaneous Gene Editing by Injection of mRNAs Encoding Transcription Activator-Like Effector Nucleases into Mouse Zygotes

Chunliang Li et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Yanfang Fu et al.

NATURE BIOTECHNOLOGY (2014)

Article Biotechnology & Applied Microbiology

Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing

Shengdar Q. Tsai et al.

NATURE BIOTECHNOLOGY (2014)

Article Biotechnology & Applied Microbiology

Fusion of catalytically inactive Cas9 to Fokl nuclease improves the specificity of genome modification

John P. Guilinger et al.

NATURE BIOTECHNOLOGY (2014)

Article Biochemical Research Methods

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

John P. Guilinger et al.

NATURE METHODS (2014)

Letter Biochemical Research Methods

E-CRISP: fast CRISPR target site identification

Florian Heigwer et al.

NATURE METHODS (2014)

Review Genetics & Heredity

A guide to genome engineering with programmable nucleases

Hyongbum Kim et al.

NATURE REVIEWS GENETICS (2014)

Article Biochemistry & Molecular Biology

De novo prediction of DNA-binding specificities for Cys(2)His(2) zinc finger proteins

Anton V. Persikov et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

Tessa G. Montague et al.

NUCLEIC ACIDS RESEARCH (2014)

Review Genetics & Heredity

Genome Engineering at the Dawn of the Golden Age

David J. Segal et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 14 (2013)

Article Biochemical Research Methods

TALENoffer: genome-wide TALEN off-target prediction

Jan Grau et al.

BIOINFORMATICS (2013)

Review Biotechnology & Applied Microbiology

Transcription activator-like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing

Ning Sun et al.

BIOTECHNOLOGY AND BIOENGINEERING (2013)

Article Biochemistry & Molecular Biology

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran et al.

Article Genetics & Heredity

Genome Engineering of Drosophila with the CRISPR RNA-Guided Cas9 Nuclease

Scott J. Gratz et al.

GENETICS (2013)

Article Biochemistry & Molecular Biology

Highly active zinc-finger nucleases by extended modular assembly

Mital S. Bhakta et al.

GENOME RESEARCH (2013)

Article Biotechnology & Applied Microbiology

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu et al.

NATURE BIOTECHNOLOGY (2013)

Article Biotechnology & Applied Microbiology

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Yanfang Fu et al.

NATURE BIOTECHNOLOGY (2013)

Article Biochemical Research Methods

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

Ari E. Friedland et al.

NATURE METHODS (2013)

Article Biochemical Research Methods

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran et al.

NATURE PROTOCOLS (2013)

Article Biochemistry & Molecular Biology

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

David Bikard et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali et al.

SCIENCE (2013)

Review Biotechnology & Applied Microbiology

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

Thomas Gaj et al.

TRENDS IN BIOTECHNOLOGY (2013)

Article Biochemistry & Molecular Biology

Exploring the DNA-recognition potential of homeodomains

Stephanie W. Chu et al.

GENOME RESEARCH (2012)

Article Biochemistry & Molecular Biology

Characterization of the DNA-binding Properties of the Mohawk Homeobox Transcription Factor

Douglas M. Anderson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemical Research Methods

An optimized two-finger archive for ZFN-mediated gene targeting

Ankit Gupta et al.

NATURE METHODS (2012)

Article Multidisciplinary Sciences

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

Le Cong et al.

NATURE COMMUNICATIONS (2012)

Article Biotechnology & Applied Microbiology

A TALE nuclease architecture for efficient genome editing

Jeffrey C. Miller et al.

NATURE BIOTECHNOLOGY (2011)

Article Biotechnology & Applied Microbiology

An unbiased genome-wide analysis of zinc-finger nuclease specificity

Richard Gabriel et al.

NATURE BIOTECHNOLOGY (2011)

Article Biochemical Research Methods

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

Vikram Pattanayak et al.

NATURE METHODS (2011)

Article Biochemistry & Molecular Biology

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity

Claudio Mussolino et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemistry & Molecular Biology

An expanded binding model for Cys2His2 zinc finger protein-DNA interfaces

Anton V. Persikov et al.

PHYSICAL BIOLOGY (2011)

Review Genetics & Heredity

Genome editing with engineered zinc finger nucleases

Fyodor D. Urnov et al.

NATURE REVIEWS GENETICS (2010)

Article Biochemical Research Methods

GADEM: A Genetic Algorithm Guided Formation of Spaced Dyads Coupled with an EM Algorithm for Motif Discovery

Leping Li

JOURNAL OF COMPUTATIONAL BIOLOGY (2009)

Article Biotechnology & Applied Microbiology

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

Dirk Hockemeyer et al.

NATURE BIOTECHNOLOGY (2009)

Article Biochemistry & Molecular Biology

Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification

Morgan L. Maeder et al.

MOLECULAR CELL (2008)

Article Biotechnology & Applied Microbiology

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells

Shondra M. Pruett-Miller et al.

MOLECULAR THERAPY (2008)

Article Biotechnology & Applied Microbiology

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Elena E. Perez et al.

NATURE BIOTECHNOLOGY (2008)

Article Biotechnology & Applied Microbiology

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Xiangdong Meng et al.

NATURE BIOTECHNOLOGY (2008)

Letter Biochemical Research Methods

Unexpected failure rates for modular assembly of engineered zinc fingers

Cherie L. Ramirez et al.

NATURE METHODS (2008)

Article Biochemical Research Methods

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)

Schmidt Manfred et al.

NATURE METHODS (2007)

Article Biotechnology & Applied Microbiology

An improved zinc-finger nuclease architecture for highly specific genome editing

Jeffrey C. Miller et al.

NATURE BIOTECHNOLOGY (2007)

Article Biotechnology & Applied Microbiology

A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors

XD Meng et al.

NATURE BIOTECHNOLOGY (2005)

Article Biochemistry & Molecular Biology

Rearrangement of side-chains in a zif268 mutant highlights the complexities of zinc finger-DNA recognition

JC Miller et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)

Article Multidisciplinary Sciences

A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

JK Joung et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)