Related references
Note: Only part of the references are listed.PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer
Nisha Nagarsheth et al.
CANCER RESEARCH (2016)
Impaired Synthesis of Stromal Components in Response to Minnelide Improves Vascular Function, Drug Delivery, and Survival in Pancreatic Cancer
Sulagna Banerjee et al.
CLINICAL CANCER RESEARCH (2016)
Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction
Ende Zhao et al.
NATURE IMMUNOLOGY (2016)
Distinct miRNA profiles in normal and gastric cancer myofibroblasts and significance in Wnt signaling
Liyi Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2016)
Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy
J. M. Pitt et al.
ANNALS OF ONCOLOGY (2016)
Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation
Qian Xiao et al.
CANCER RESEARCH (2016)
Combining Epigenetic and Immunotherapy to Combat Cancer
Katherine B. Chiappinelli et al.
CANCER RESEARCH (2016)
OncomiR or Tumor Suppressor? The Duplicity of MicroRNAs in Cancer
Alexander A. Svoronos et al.
CANCER RESEARCH (2016)
Changing the course of pancreatic cancer - Focus on recent translational advances
Milind Jayle et al.
CANCER TREATMENT REVIEWS (2016)
Pancreatic cancer microenvironment, to target or not to target?
Ryan M. Carr et al.
EMBO MOLECULAR MEDICINE (2016)
Targeting the tumour microenvironment in ovarian cancer
Jean M. Hansen et al.
EUROPEAN JOURNAL OF CANCER (2016)
Carcinoma-associated fibroblasts: orchestrating the composition of malignancy
Philippe Gascard et al.
GENES & DEVELOPMENT (2016)
KATching-Up on Small Molecule Modulators of Lysine Acetyltransferases
Roman P. Simon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Essential role of miRNAs in orchestrating the biology of the tumor microenvironment
Jamie N. Frediani et al.
MOLECULAR CANCER (2016)
Targeting EZH2 in cancer
Kimberly H. Kim et al.
NATURE MEDICINE (2016)
Role of the EZH2 histone methyltransferase as a therapeutic target in cancer
Antoine Italiano
PHARMACOLOGY & THERAPEUTICS (2016)
Tumor-associated fibroblasts predominantly come from local and not circulating precursors
Ainhoa Arina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Key players in pancreatic cancer-stroma interaction: cancer-associated fibroblasts, endothelial and inflammatory cells
Michael Friberg Bruun Nielsen et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2016)
Exosome-mediated delivery of miR-9 induces cancer-associated fibroblast-like properties in human breast fibroblasts
S. Baroni et al.
CELL DEATH & DISEASE (2016)
Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling
Hua Shen et al.
PLOS GENETICS (2016)
Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to Go
Rachel J. Buchsbaum et al.
CANCERS (2016)
Cross Talk between Cancer and Mesenchymal Stem Cells through extracellular vesicles Carrying Nucleic Acids
Tatiana Lopatina et al.
FRONTIERS IN ONCOLOGY (2016)
MicroRnA Targeting to Modulate Tumor Microenvironment
Praneeth R. Kuninty et al.
FRONTIERS IN ONCOLOGY (2016)
Isolation of Epithelial, Endothelial, and Immune Cells from Lungs of Transgenic Mice with Oncogene-Induced Lung Adenocarcinomas
Amlak Bantikassegn et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
Targeting Histone Deacetylases in Diseases: Where Are We?
Rosaria Benedetti et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
Jerome Paggetti et al.
BLOOD (2015)
DNA demethylation and invasive cancer: implications for therapeutics
David Cheishvili et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype
Sanket H. Shah et al.
CANCER BIOLOGY & THERAPY (2015)
Pancreatic cancer-secreted miR-155 implicates in the conversion from normal fibroblasts to cancer-associated fibroblasts
Wenjing Pang et al.
CANCER SCIENCE (2015)
Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment
Pu Li et al.
CELL RESEARCH (2015)
Digging deep into dirty'' drugs - modulation of the methylation machinery
Lisa Pleyer et al.
DRUG METABOLISM REVIEWS (2015)
Metabolic reprogramming of the tumour microenvironment
Yazhi Xing et al.
FEBS JOURNAL (2015)
Stromal biology and therapy in pancreatic cancer: a changing paradigm
Albrecht Neesse et al.
GUT (2015)
Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity
Stuti Mehta et al.
IMMUNOLOGY AND CELL BIOLOGY (2015)
Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer
Daniel V. T. Catenacci et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Tumor necrosis factor-related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype
Jing Gao et al.
MOLECULAR BIOLOGY OF THE CELL (2015)
Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
Dongjun Peng et al.
NATURE (2015)
MicroRNAs as mediators and communicators between cancer cells and the tumor microenvironment
F. J. Kohlhapp et al.
ONCOGENE (2015)
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation
Ke Liu et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity
Jie Yin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Notch in T Cell Differentiation: All Things Considered
Derk Amsen et al.
TRENDS IN IMMUNOLOGY (2015)
Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts
Jean Albrengues et al.
NATURE COMMUNICATIONS (2015)
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor Growth
Kazuyoshi Shiga et al.
CANCERS (2015)
Targeting the histone orthography of cancer: drugs for writers, erasers and readers
Laia Simo-Riudalbas et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment
Jana Jeschke et al.
FEBS JOURNAL (2015)
Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis
S. Josson et al.
ONCOGENE (2015)
The Narrow-Spectrum HDAC Inhibitor Entinostat Enhances NKG2D Expression Without NK Cell Toxicity, Leading to Enhanced Recognition of Cancer Cells
Shiguo Zhu et al.
PHARMACEUTICAL RESEARCH (2015)
Epigenetic Changes during Hepatic Stellate Cell Activation
Silke Goetze et al.
PLOS ONE (2015)
TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer
Jose A. Galvan et al.
ONCOTARGET (2015)
Epigenetic control of myeloid cell differentiation, identity and function
Damiana Alvarez-Errico et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells
Nami Yamada et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells
Ki Cheong Park et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Enhanced shedding of extracellular vesicles from amoeboid prostate cancer cells Potential effects on the tumor microenvironment
Jayoung Kim et al.
CANCER BIOLOGY & THERAPY (2014)
Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer
Xiaojing Yang et al.
CANCER CELL (2014)
Epigenetic targeting in pancreatic cancer
Jasmijn G. M. van Kampen et al.
CANCER TREATMENT REVIEWS (2014)
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth
Yuan Yin et al.
CELL RESEARCH (2014)
Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203
Min Zhou et al.
CELLULAR IMMUNOLOGY (2014)
MicroRNA-106b in cancer-associated fibroblasts from gastric cancer promotes cell migration and invasion by targeting PTEN
Ting-Song Yang et al.
FEBS LETTERS (2014)
Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance
Hariharan Easwaran et al.
MOLECULAR CELL (2014)
Epigenetics and Oncology
Padmaja Mummaneni et al.
PHARMACOTHERAPY (2014)
Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats
Er-Bao Bian et al.
TOXICOLOGY LETTERS (2014)
Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer
Upasana Bedi et al.
ONCOTARGET (2014)
MicroRNAs: Promising New Antiangiogenic Targets in Cancer
Sandra Gallach et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Desmoplasia and Chemoresistance in Pancreatic Cancer
Marvin Schober et al.
CANCERS (2014)
Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast cancer
Fahimeh Falahi et al.
BREAST CANCER RESEARCH (2014)
Cancer Associated Fibroblasts express pro-inflammatory factors in human breast and ovarian tumors
Neta Erez et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Docetaxel Conjugate Nanoparticles That Target α-Smooth Muscle Actin-Expressing Stromal Cells Suppress Breast Cancer Metastasis
Mami Murakami et al.
CANCER RESEARCH (2013)
microRNA-mediated regulation of the tumor microenvironment
Jonathan Chou et al.
CELL CYCLE (2013)
Epigenetic modulation of the immune function A potential target for tolerance
Beatriz Suarez-Alvarez et al.
EPIGENETICS (2013)
A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling
Yuqing Liu et al.
LIVER INTERNATIONAL (2013)
Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility
O. Aprelikova et al.
ONCOGENE (2013)
'Cancer associated fibroblasts' - more than meets the eye
Shalom Madar et al.
TRENDS IN MOLECULAR MEDICINE (2013)
Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression
M. D. Bullock et al.
CELL DEATH & DISEASE (2013)
Isolation and genome-wide expression and methylation characterization of CD31+ cells from normal and malignant human prostate tissue
Wei Luo et al.
ONCOTARGET (2013)
Recent Developments in Myofibroblast Biology Paradigms for Connective Tissue Remodeling
Boris Hinz et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
Ali Shilatifard
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
The Pancreas Cancer Microenvironment
Christine Feig et al.
CLINICAL CANCER RESEARCH (2012)
Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation
Maria Jesus Perugorria et al.
HEPATOLOGY (2012)
Cancer-Associated Fibroblasts Drive the Progression of Metastasis through both Paracrine and Mechanical Pressure on Cancer Tissue
George S. Karagiannis et al.
MOLECULAR CANCER RESEARCH (2012)
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
A. Bronisz et al.
NATURE CELL BIOLOGY (2012)
Understanding the language of Lys36 methylation at histone H3
Eric J. Wagner et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change
Shiaw-Wei Tyan et al.
PLOS ONE (2012)
Unlike Pancreatic Cancer Cells Pancreatic Cancer Associated Fibroblasts Display Minimal Gene Induction after 5-Aza-2′-Deoxycytidine
Jun Yu et al.
PLOS ONE (2012)
DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats
Er-Bao Bian et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)
MicroRNAs Reprogram Normal Fibroblasts into Cancer-Associated Fibroblasts in Ovarian Cancer
Anirban K. Mitra et al.
CANCER DISCOVERY (2012)
Genome-Wide Analysis of Promoter Methylation Associated with Gene Expression Profile in Pancreatic Adenocarcinoma
Audrey Vincent et al.
CLINICAL CANCER RESEARCH (2011)
Anti-stromal therapy with imatinib inhibits growth and metastasis of gastric carcinoma in an orthotopic nude mouse model
Tomonori Sumida et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
Mei Yang et al.
MOLECULAR CANCER (2011)
Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer
M. Musumeci et al.
ONCOGENE (2011)
Cervical carcinoma-associated fibroblasts are DNA diploid and do not show evidence for somatic genetic alterations
Willem Ernst Corver et al.
CELLULAR ONCOLOGY (2011)
Inflammatory Alterations of the Extracellular Matrix in the Tumor Microenvironment
Junko Iijima et al.
Cancers (2011)
SWI/SNF nucleosome remodellers and cancer
Boris G. Wilson et al.
NATURE REVIEWS CANCER (2011)
Breast Carcinoma-Associated Fibroblasts Rarely Contain p53 Mutations or Chromosomal Aberrations
Abdel Nasser Hosein et al.
CANCER RESEARCH (2010)
The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts
Olga Aprelikova et al.
CELL CYCLE (2010)
Overexpression of Smoothened Activates the Sonic Hedgehog Signaling Pathway in Pancreatic Cancer-Associated Fibroblasts
Kimberly Walter et al.
CLINICAL CANCER RESEARCH (2010)
Epigenetic regulation of cancer growth by histone demethylases
Soyoung Lim et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Cancer associated fibroblasts in cancer pathogenesis
Omar E. Franco et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
Cancer-associated fibroblasts and tumor growth - bystanders turning into key players
Arne Oestman et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
Angelica M. Santos et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Pten in stromal fibroblasts suppresses mammary epithelial tumours
Anthony J. Trimboli et al.
NATURE (2009)
Global Hypomethylation of Genomic DNA in Cancer-Associated Myofibroblasts
Le Jiang et al.
CANCER RESEARCH (2008)
Stromal myofibroblasts are drivers of invasive cancer growth
Olivier De Wever et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
CpG methylation of the IFNG gene as a mechanism to induce immunosupression in tumor-infiltrating lymphocytes
Peter C. J. Janson et al.
JOURNAL OF IMMUNOLOGY (2008)
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
Wen Qiu et al.
NATURE GENETICS (2008)
Hepatic stellate cells: Protean, multifunctional, and enigmatic cells of the liver
Scott L. Friedman
PHYSIOLOGICAL REVIEWS (2008)
Breast-cancer stromal cells with TP53 mutations and nodal metastases
Attila Patocs et al.
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Antifibrogenic effects of histone deacetylase inhibitors on pancreatic stellate cells
Robin Buelow et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Genomic instability within tumor stroma and clinicopathological characteristics of sporadic primary invasive breast carcinoma
Koichi Fukino et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Identification of epigenetically silenced genes in tumor endothelial cells
Debby M. E. I. Hellebrekers et al.
CANCER RESEARCH (2007)
Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol
Ivy Chung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
Yeshayahu Schlesinger et al.
NATURE GENETICS (2007)
Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis
J. Mann et al.
CELL DEATH AND DIFFERENTIATION (2007)
Microenvironmental genomic alterations and clinicopathological behavior in head and neck squamous cell carcinoma
Frank Weber et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Inhibition of Smad3 expression decreases collagen synthesis in keloid disease fibroblasts
Zimin Wang et al.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2007)
Cancer epigenomics: DNA methylomes and histone-modification maps
Manel Esteller
NATURE REVIEWS GENETICS (2007)
Smad3 as a mediator of the fibrotic response
KC Flanders
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2004)
Cytoplasmic PML function in TGF-β signalling
HK Lin et al.
NATURE (2004)
A novel model to study renal myofibroblast formation in vitro
C Grupp et al.
KIDNEY INTERNATIONAL (2001)