4.4 Article

Diagnostic value of contrast-enhanced ultrasound in papillary thyroid microcarcinoma

Journal

EXPERIMENTAL AND THERAPEUTIC MEDICINE
Volume 11, Issue 5, Pages 1555-1562

Publisher

SPANDIDOS PUBL LTD
DOI: 10.3892/etm.2016.3094

Keywords

thyroid papillary microcarcinoma; contrast-enhanced ultrasonography; diagnosis

Funding

  1. SJTU Medicine Engineering Interdisciplinary Research Fund [YG2013MS53]
  2. Shanghai Municipal Natural Science Foundation [12ZR1422600]
  3. National Nature Science Foundation of China [81371574]
  4. Research Fund for the Doctoral Program of Higher Education of Chinam [20120073120100]

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The aim of the present study was to explore the value and characteristics of contrast-enhanced ultrasound (CEUS) in the diagnosis of papillary thyroid microcarcinoma (PTMC). By analyzing CEUS information of 130 nodules obtained from 106 patients with PTMC, who had been diagnosed by surgery and pathological analysis, CEUS characteristics of PTMC nodules were concluded. Based on the results, the PTMC nodules were divided into three groups as follows: 32 nodules (24.62%) were found to be enhanced earlier than the surrounding normal thyroid tissue, 95 nodules (73.08%) were enhanced at the same time as the normal thyroid tissue and 3 nodules (2.30%) were enhanced later than the normal thyroid tissue. The results also demonstrated that the peak enhancement intensity of the 130 nodules was lower compared with the irregular intensity of the normal parenchyma in corresponding thyroids, and that PTMC enhancement washed out faster than in normal thyroid parenchyma. In conclusion, the PTMC characteristics that CEUS can detect may improve the diagnostic accuracy and provide valuable information for the treatment of the disease.

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