Journal
SAUDI PHARMACEUTICAL JOURNAL
Volume 24, Issue 1, Pages 1-20Publisher
ELSEVIER
DOI: 10.1016/j.jsps.2013.12.003
Keywords
Microelectromechanical system; Drug delivery; Microfabrication
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Advancement in microelectromechanical system has facilitated the microfabrication of polymeric substrates and the development of the novel class of controlled drug delivery devices. These vehicles have specifically tailored three dimensional physical and chemical features which together, provide the capacity to target cell, stimulate unidirectional controlled release of therapeutics and augment permeation across the barriers. Apart from drug delivery devices microfabrication technology's offer exciting prospects to generate biomimetic gastrointestinal tract models. BioMEMS are capable of analysing biochemical liquid sample like solution of metabolites, macromolecules, proteins, nucleic acid, cells and viruses. This review summarized multidisciplinary application of biomedical microelectromechanical systems in drug delivery and its potential in analytical procedures. (c) 2013 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.
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