Related references
Note: Only part of the references are listed.Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin
Alexander V. Peskin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Effective Killing of Cancer Cells Through ROS-Mediated Mechanisms by AMRI-59 Targeting Peroxiredoxin I
Yeon Ju Yang et al.
ANTIOXIDANTS & REDOX SIGNALING (2016)
Involvement of aquaporin-3 in epidermal growth factor receptor signaling via hydrogen peroxide transport in cancer cells
Mariko Hara-Chikuma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer
Jong-Lyel Roh et al.
CANCER LETTERS (2016)
Ferroptosis: process and function
Y. Xie et al.
CELL DEATH AND DIFFERENTIATION (2016)
Ferrootosis: Death by Lipid Peroxidation
Wan Seok Yang et al.
TRENDS IN CELL BIOLOGY (2016)
A Chemical Approach for the Detection of Protein Sulfinylation
Mauro Lo Conte et al.
ACS CHEMICAL BIOLOGY (2015)
Pro-oxidant activity of polyphenols and its implication on cancer chemoprevention and chemotherapy
Antonio J. Leon-Gonzalez et al.
BIOCHEMICAL PHARMACOLOGY (2015)
Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner
Bing Yan et al.
BMC CANCER (2015)
Mediterranean diet and risk of endometrial cancer: a pooled analysis of three italian case-control studies
M. Filomeno et al.
BRITISH JOURNAL OF CANCER (2015)
Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth
Lingtao Jin et al.
CANCER CELL (2015)
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Isaac S. Harris et al.
CANCER CELL (2015)
Metastasis and Oxidative Stress: Are Antioxidants a Metabolic Driver of Progression?
Maria Peiris-Pages et al.
CELL METABOLISM (2015)
ROS signaling and redox biology in endothelial cells
Emiliano Panieri et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
ROS-Mediated DNA Methylation Pattern Alterations in Carcinogenesis
Qihan Wu et al.
CURRENT DRUG TARGETS (2015)
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Yan Xiang et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Glutaminolysis and Transferrin Regulate Ferroptosis
Minghui Gao et al.
MOLECULAR CELL (2015)
CANCER The enemy of my enemy is my friend
Isaac S. Harris et al.
NATURE (2015)
Oxidative stress inhibits distant metastasis by human melanoma cells
Elena Piskounova et al.
NATURE (2015)
NRF2 regulates serine biosynthesis in non-small cell lung cancer
Gina M. DeNicola et al.
NATURE GENETICS (2015)
Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
B. Schenk et al.
ONCOGENE (2015)
Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling
Arden Perkins et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation
K. Kluckova et al.
CELL DEATH & DISEASE (2015)
Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma
Giuseppe Lucarelli et al.
ONCOTARGET (2015)
The redox biology network in cancer pathophysiology and therapeutics
Gina Manda et al.
REDOX BIOLOGY (2015)
Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction
N. Cetinbas et al.
ONCOGENE (2015)
Synthetic lethality of combined glutaminase and Hsp90 inhibition in mTORC1-driven tumor cells
Jing Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Glutaredoxin 2 Reduces Both Thioredoxin 2 and Thioredoxin 1 and Protects Cells from Apoptosis Induced by Auranofin and 4-Hydroxynonenal
Huihui Zhang et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Targeting antioxidants for cancer therapy
Andrea Glasauer et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death
Li Yin et al.
BLOOD (2014)
Importance of Glutamine Metabolism in Leukemia Cells by Energy Production Through TCA Cycle and by Redox Homeostasis
Mineaki Goto et al.
CANCER INVESTIGATION (2014)
2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy
Dongsheng Zhang et al.
CANCER LETTERS (2014)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
ROS Function in Redox Signaling and Oxidative Stress
Michael Schieber et al.
CURRENT BIOLOGY (2014)
Glutamine, Glucose and other Fuels for Cancer
Maria Victoria Ruiz-Perez et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations
Ashkan Emadi et al.
EXPERIMENTAL HEMATOLOGY (2014)
The thioredoxin antioxidant system
Jun Lu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
Caroline A. Lewis et al.
MOLECULAR CELL (2014)
Quantitative flux analysis reveals folate-dependent NADPH production
Jing Fan et al.
NATURE (2014)
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Edward T. Chouchani et al.
NATURE (2014)
Repurposing biguanides to target energy metabolism for cancer treatment
Michael Pollak
NATURE MEDICINE (2014)
Cellular mechanisms and physiological consequences of redox-dependent signalling
Kira M. Holmstroem et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
Andreas Janzer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Serine and glycine metabolism in cancer
Ivano Amelio et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
The pentose phosphate pathway and cancer
Krushna C. Patra et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-XL/p53-mediated amplification mechanisms
Y-L Shi et al.
CELL DEATH & DISEASE (2014)
Redox control of glutamine utilization in cancer
L. Alberghina et al.
CELL DEATH & DISEASE (2014)
Mitochondrial One-Carbon Metabolism Maintains Redox Balance during Hypoxia
Inmaculada Martinez-Reyes et al.
CANCER DISCOVERY (2014)
Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
Jiangbin Ye et al.
CANCER DISCOVERY (2014)
Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense
Angelo D'Alessandro et al.
ONCOTARGET (2014)
A Mitochondrial Switch Promotes Tumor Metastasis
Paolo E. Porporato et al.
CELL REPORTS (2014)
Regulation of the pentose phosphate pathway in cancer
Peng Jiang et al.
PROTEIN & CELL (2014)
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton et al.
ELIFE (2014)
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
Scott J. Dixon et al.
ELIFE (2014)
Mitochondrial reactive oxygen species and cancer
Lucas B. Sullivan et al.
CANCER & METABOLISM (2014)
Thioredoxins, Glutaredoxins, and Peroxiredoxins-Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling
Eva-Maria Hanschmann et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Hydrogen peroxide inhibits transforming growth factor-β1-induced cell cycle arrest by promoting Smad3 linker phosphorylation through activation of Akt-ERK1/2-linked signaling pathway
Jiyeon Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK
Y. Storozhuk et al.
BRITISH JOURNAL OF CANCER (2013)
LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin
David B. Shackelford et al.
CANCER CELL (2013)
PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress
Francisca Vazquez et al.
CANCER CELL (2013)
Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF
Rizwan Haq et al.
CANCER CELL (2013)
Dual Role of the Antioxidant Enzyme Peroxiredoxin 6 in Skin Carcinogenesis
Frank Rolfs et al.
CANCER RESEARCH (2013)
Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance
Costas A. Lyssiotis et al.
CELL CYCLE (2013)
Cellular Fatty Acid Metabolism and Cancer
Erin Currie et al.
CELL METABOLISM (2013)
Glutaminase Isoenzymes as Key Regulators in Metabolic and Oxidative Stress Against Cancer
J.M. Mates et al.
CURRENT MOLECULAR MEDICINE (2013)
Thioredoxin 1 Is Inactivated Due to Oxidation Induced by Peroxiredoxin under Oxidative Stress and Reactivated by the Glutaredoxin System
Yatao Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Glutamine and cancer: cell biology, physiology, and clinical opportunities
Christopher T. Hensley et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Glutamine-driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia
Jing Fan et al.
MOLECULAR SYSTEMS BIOLOGY (2013)
Sensitization of pancreatic cancer cells to radiation by cerium oxide nanoparticle-induced ROS production
Melissa S. Wason et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2013)
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Jaekyoung Son et al.
NATURE (2013)
TAp73 enhances the pentose phosphate pathway and supports cell proliferation
Wenjing Du et al.
NATURE CELL BIOLOGY (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Role of antioxidants in cancer therapy
Vanessa Fuchs-Tarlovsky
NUTRITION (2013)
Cisplatin Induces a Mitochondrial-ROS Response That Contributes to Cytotoxicity Depending on Mitochondrial Redox Status and Bioenergetic Functions
Rossella Marullo et al.
PLOS ONE (2013)
Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma
Ping Yuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Glutaredoxin regulates vascular development by reversible glutathionylation of sirtuin 1
Lars Brautigam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion
Laura Lehtinen et al.
ONCOTARGET (2013)
Serine, glycine and one-carbon units: cancer metabolism in full circle
Jason W. Locasale
NATURE REVIEWS CANCER (2013)
Cancer metabolism: fatty acid oxidation in the limelight
Arkaitz Carracedo et al.
NATURE REVIEWS CANCER (2013)
Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APCMin/+ Mice
Dong Kyun Woo et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Mitochondrial Thiols in Antioxidant Protection and Redox Signaling: Distinct Roles for Glutathionylation and Other Thiol Modifications
Michael P. Murphy
ANTIOXIDANTS & REDOX SIGNALING (2012)
Redox Regulation of Mitochondrial Function
Diane E. Handy et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels
Michael S. Lustgarten et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Phenformin as prophylaxis and therapy in breast cancer xenografts
M. V. C. L. Appleyard et al.
BRITISH JOURNAL OF CANCER (2012)
Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma
Pilar Caro et al.
CANCER CELL (2012)
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
Patrick S. Ward et al.
CANCER CELL (2012)
Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
Gang Cheng et al.
CANCER RESEARCH (2012)
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
Anne Le et al.
CELL METABOLISM (2012)
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
Paul D. Ray et al.
CELLULAR SIGNALLING (2012)
The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate
Chiara Riganti et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Signal Transduction by Mitochondrial Oxidants
Toren Finkel
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions
Casey L. Quinlan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Metformin in cancer: translational challenges
Ryan J. O. Dowling et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2012)
Inactivation of a Peroxiredoxin by Hydrogen Peroxide Is Critical for Thioredoxin-Mediated Repair of Oxidized Proteins and Cell Survival
Alison M. Day et al.
MOLECULAR CELL (2012)
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
Sang-Min Jeon et al.
NATURE (2012)
Targeting cancer metabolism: a bedside lesson
Kivanc Birsoy et al.
NATURE MEDICINE (2012)
Glutathione Depletion and Carbon Ion Radiation Potentiate Clustered DNA Lesions, Cell Death and Prevent Chromosomal Changes in Cancer Cells Progeny
Maite Hanot et al.
PLOS ONE (2012)
Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription
Abu-Bakr Al-Mehdi et al.
SCIENCE SIGNALING (2012)
Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
Dania Daye et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)
A combination of 2-deoxy-D-glucose and 6-aminonicotinamide induces cell cycle arrest and apoptosis selectively in irradiated human malignant cells
Richa Bhardwaj et al.
TUMOR BIOLOGY (2012)
Radical Decisions in Cancer: Redox Control of Cell Growth and Death
Rosa M. Sainz et al.
Cancers (2012)
Redox-Active Quinones and Ascorbate: An Innovative Cancer Therapy That Exploits the Vulnerability of Cancer Cells to Oxidative Stress
Julien Verrax et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2011)
Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity
Manuela Polimeni et al.
BIOCHEMICAL JOURNAL (2011)
Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
Lisa S. Pike et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2011)
Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
Marko Skrtic et al.
CANCER CELL (2011)
Serine Metabolism: Some Tumors Take the Road Less Traveled
Ralph J. DeBerardinis
CELL METABOLISM (2011)
In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
Frederick Daidone et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2011)
Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumors
Ching-Chuan Kuo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells
Tomohiro Itoh et al.
FREE RADICAL RESEARCH (2011)
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
Kathrin Zaugg et al.
GENES & DEVELOPMENT (2011)
Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation
Lokendra Kumar Sharma et al.
HUMAN MOLECULAR GENETICS (2011)
Mitochondrial reactive oxygen species drive proinflammatory cytokine production
Edwina Naik et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
Gina M. De Nicola et al.
NATURE (2011)
被撤回的出版物: Selective killing of cancer cells by a small molecule targeting the stress response to ROS (Retracted article. See vol. 561, pg. 420, 2018)
Lakshmi Raj et al.
NATURE (2011)
Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2
J. Chen et al.
ONCOGENE (2011)
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
Alice T. Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism
Dongmei Ren et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Animal and human studies with the mitochondria-targeted antioxidant MitoQ
Robin A. J. Smith et al.
MITOCHONDRIAL RESEARCH IN TRANSLATIONAL MEDICINE (2010)
A Model of Redox Kinetics Implicates the Thiol Proteome in Cellular Hydrogen Peroxide Responses
Nnenna J. Adimora et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance
Anju Singh et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Glutathione depletion enhances arsenic trioxide-induced apoptosis in lymphoma cells through mitochondrial-independent mechanisms
Savita Bhalla et al.
BRITISH JOURNAL OF HAEMATOLOGY (2010)
Metabolic oxidative stress induced by a combination of 2-DG and 6-AN enhances radiation damage selectively in malignant cells via non-coordinated expression of antioxidant enzymes
Pradeep K. Sharma et al.
CANCER LETTERS (2010)
Metformin Prevents Tobacco Carcinogen-Induced Lung Tumorigenesis
Regan M. Memmott et al.
CANCER PREVENTION RESEARCH (2010)
Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1
Meghan J. Seltzer et al.
CANCER RESEARCH (2010)
The Antioxidant Transcription Factor Nrf2 Negatively Regulates Autophagy and Growth Arrest Induced by the Anticancer Redox Agent Mitoquinone
V. Ashutosh Rao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
Ismael Samudio et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
R. J. DeBerardinis et al.
ONCOGENE (2010)
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Anne Le et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
Frank Weinberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
Arnold J. Levine et al.
SCIENCE (2010)
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation
Nukhet Aykin-Burns et al.
BIOCHEMICAL JOURNAL (2009)
Targeted depletion of BMI1 sensitizes tumor cells to P53-mediated apoptosis in response to radiation therapy
N. M. Alajez et al.
CELL DEATH AND DIFFERENTIATION (2009)
Superoxide is the major reactive oxygen species regulating autophagy
Y. Chen et al.
CELL DEATH AND DIFFERENTIATION (2009)
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Zachary T. Schafer et al.
NATURE (2009)
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Ping Gao et al.
NATURE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Tumor cell metabolism: Cancer's Achilles' heel
Guido Kroemer et al.
CANCER CELL (2008)
Increased chemosensitivity and elevated reactive oxygen species are mediated by glutathione reduction in glutamine deprived neuroblastoma cells
Sakurako Izaki et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2008)
Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
Brian Clem et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
Jeffrey A. Engelman et al.
NATURE MEDICINE (2008)
Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling
Jose C. Juarez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
David R. Wise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
Kaori Ishikawa et al.
SCIENCE (2008)
HIF-dependent antitumorigenic effect of antioxidants in vivo
Ping Gao et al.
CANCER CELL (2007)
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
Jun Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
4-Hydroxynonenal and PPARγ ligands affect proliferation, differentiation, and apoptosis in colon cancer cells
Angelo Cerbone et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Differential subcellular distribution of glucose transporters GLUT1-6 and GLUT9 in human cancer:: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues
A Godoy et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
Lothar Kussmaul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Phonformin-induced lactic acidosis in an older diabetic patient
FL Fimognari et al.
DIABETES CARE (2006)
Nox enzymes and the biology of reactive oxygen
JD Lambeth
NATURE REVIEWS IMMUNOLOGY (2004)
Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol
D Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Reversible inactivation of the tumor suppressor PTEN by H2O2
SR Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
O Vafa et al.
MOLECULAR CELL (2002)
Reactive oxygen species as double-edged swords in cellular processes: low-dose cell signaling versus high-dose toxicity
KR Martin et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2002)
1-Cys peroxiredoxin, a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities
JW Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
