4.8 Article

Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?

Journal

CHEMICAL SCIENCE
Volume 7, Issue 3, Pages 2011-2015

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5sc02319j

Keywords

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Funding

  1. Dutch Ministry of Education, Culture and Science [024.001.035]
  2. European Research Council [246829]
  3. NIH
  4. NSF through MRSEC [DMR 111053]
  5. NSF
  6. UCSB-CISEI program through the NSF Research Experiences for Undergraduates [NSF DMR 0843934]
  7. Direct For Mathematical & Physical Scien [0843934] Funding Source: National Science Foundation
  8. Division Of Materials Research [0843934] Funding Source: National Science Foundation

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A library of water-soluble dynamic single-chain polymeric nanoparticles (SCPN) was prepared using a controlled radical polymerisation technique followed by the introduction of functional groups, including probes at targeted positions. The combined tools of electron paramagnetic resonance (EPR) and Overhauser dynamic nuclear polarization (ODNP) reveal that these SCPNs have structural and surface hydration properties resembling that of enzymes.

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