Journal
CHEMICAL SCIENCE
Volume 7, Issue 10, Pages 6309-6315Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6sc02500e
Keywords
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Funding
- 973 Program [2015CB932001, 2015CB856301]
- NSF of China [21535009, 21435007, 21321003]
- Chinese Academy of Sciences [XDB14030102]
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Spectroscopic (chromogenic, fluorescent, or chemiluminescent) probes have been widely used in many fields due to their high sensitivity and unrivaled spatiotemporal resolution. This area is an old one but always full of activity, because the rapid development of science and technology requires not only new probes for specific purposes (e.g., subcellular imaging) but also the update of current probes with more satisfactory properties. Based on our experiences and including existing knowledge, in this mini-review we briefly discuss the design strategies, response modes, and bioapplications of small molecular spectroscopic probes, in particular their advantages and disadvantages as well as possible research trends, which may be helpful to those who are interested in this continually growing research area.
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