Related references
Note: Only part of the references are listed.Hydrocarbon Stapled Peptides as Modulators of Biological Function
Philipp M. Cromm et al.
ACS CHEMICAL BIOLOGY (2015)
α-Peptide-Oligourea Chimeras: Stabilization of Short α-Helices by Non-Peptide Helical Foldamers
Juliette Fremaux et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
Peptide stapling techniques based on different macrocyclisation chemistries
Yu Heng Lau et al.
CHEMICAL SOCIETY REVIEWS (2015)
α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells
James W. Checco et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Receptor-templated stapling of intrinsically disordered peptide ligands
Conor M. Haney et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
Towards understanding cell penetration by stapled peptides
Qian Chu et al.
MEDCHEMCOMM (2015)
Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies
Greg H. Bird et al.
ACS CHEMICAL BIOLOGY (2014)
Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction
Christopher H. Douse et al.
ACS CHEMICAL BIOLOGY (2014)
Direct Targeting of Rab-GTPase-Effector Interactions**
Jochen Spiegel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Simultaneous Inhibition of Key Growth Pathways in Melanoma Cells and Tumor Regression by a Designed Bidentate Constrained Helical Peptide
Amlanjyoti Dhar et al.
BIOPOLYMERS (2014)
Tailor-Made Designer Helical Peptides that Induce Mitochondrion-Mediated Cell Death without Necrosis
Kagayaki Nogami et al.
CHEMBIOCHEM (2014)
Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
Michelle R. Arkin et al.
CHEMISTRY & BIOLOGY (2014)
Discovery of a Potent Stapled Helix Peptide That Binds to the 70N Domain of Replication Protein A
Andreas O. Frank et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress
Loren D. Walensky et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Coupled Folding and Binding of the Disordered Protein PUMA Does Not Require Particular Residual Structure
Joseph M. Rogers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
Peter E. Czabotar et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
X. Xie et al.
ONCOGENE (2014)
Effects of side chains in helix nucleation differ from helix propagation
Stephen E. Miller et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein
Joseph M. Rogers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Many players in BCL-2 family affairs
Tudor Moldoveanu et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Functionalised staple linkages for modulating the cellular activity of stapled peptides
Yu Heng Lau et al.
CHEMICAL SCIENCE (2014)
Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity
Toru Okamoto et al.
ACS CHEMICAL BIOLOGY (2013)
Monosubstituted alkenyl amino acids for peptide stapling
David J. Yeo et al.
CHEMICAL COMMUNICATIONS (2013)
Inhibition of α-helix-mediated protein-protein interactions using designed molecules
Valeria Azzarito et al.
NATURE CHEMISTRY (2013)
Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling
Swati Kushal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces
Dilraj Lama et al.
SCIENTIFIC REPORTS (2013)
A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers
James L. LaBelle et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Design of Triazole-Stapled BCL9 α-Helical Peptides to Target the β-Catenin/B-Cell CLL/lymphoma 9 (BCL9) Protein-Protein Interaction
Steven A. Kawamoto et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Rational Design of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors
Avinash Muppidi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Development of α-Helical Calpain Probes by Mimicking a Natural Protein-Protein Interaction
Hyunil Jo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Structural Basis of Bcl-xL Recognition by a BH3-Mimetic α/β-Peptide Generated by Sequence-Based Design
Erinna F. Lee et al.
CHEMBIOCHEM (2011)
Design and Structure of Stapled Peptides Binding to Estrogen Receptors
Chris Phillips et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer
Michelle L. Stewart et al.
NATURE CHEMICAL BIOLOGY (2010)
Introduction of All-Hydrocarbon i,i+3 Staples into α-Helices via Ring-Closing Olefin Metathesis
Young-Woo Kim et al.
ORGANIC LETTERS (2010)
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency
Rosemary S. Harrison et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Induced fit, conformational selection and independent dynamic segments: an extended view of binding events
Peter Csermely et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
BCL-2 family antagonists for cancer therapy
Guillaume Lessene et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Structural insights into the degradation of Mcl-1 induced by BH3 domains
Peter E. Czabotar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A stapled BID BH3 helix directly binds and activates BAX
Loren D. Walensky et al.
MOLECULAR CELL (2006)
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
Michael Certo et al.
CANCER CELL (2006)
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
L Chen et al.
MOLECULAR CELL (2005)
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
LD Walensky et al.
SCIENCE (2004)
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein - Protein interactions by fluorescence polarization
MHA Roehrl et al.
BIOCHEMISTRY (2004)
Understanding noncovalent interactions: Ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes
DH Williams et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
AM Leduc et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cooperativity, partially bound states, and enthalpy-entropy compensation
CA Hunter et al.
CHEMISTRY & BIOLOGY (2003)
Short constrained peptides that inhibit HIV-1 entry
SK Sia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides
CE Schafmeister et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Share Paper
