Journal
VIRUSES-BASEL
Volume 8, Issue 10, Pages -Publisher
MDPI AG
DOI: 10.3390/v8100270
Keywords
hepatitis E virus (HEV); animals; zoonotic reservoir; foodborne transmission
Categories
Funding
- European Union Seventh Framework Program (FP7) [278433-PREDEMICS]
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During the past ten years, several new hepatitis E viruses (HEVs) have been identified in various animal species. In parallel, the number of reports of autochthonous hepatitis E in Western countries has increased as well, raising the question of what role these possible animal reservoirs play in human infections. The aim of this review is to present the recent discoveries of animal HEVs and their classification within the Hepeviridae family, their zoonotic and species barrier crossing potential, and possible use as models to study hepatitis E pathogenesis. Lastly, this review describes the transmission pathways identified from animal sources.
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