Journal
VIRUSES-BASEL
Volume 8, Issue 9, Pages -Publisher
MDPI AG
DOI: 10.3390/v8090248
Keywords
HIV-1; packaging; Gag; genomic RNA; assembly
Categories
Funding
- Sidaction
- French Agence Nationale de Recherches sur le SIDA et les Hepatites Virales (ANRS)
- ANRS
- Initiative d'excellence (IDEX), Par-dela les frontieres, l'Universite de Strasbourg
- Fondation pour la Recherche Medicale en France [FDT20160435353]
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Human immunodeficiency virus type 1 (HIV-1) replication is a highly regulated process requiring the recruitment of viral and cellular components to the plasma membrane for assembly into infectious particles. This review highlights the recent process of understanding the selection of the genomic RNA (gRNA) by the viral Pr55(Gag) precursor polyprotein, and the processes leading to its incorporation into viral particles.
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