Journal
CLINICAL INFECTIOUS DISEASES
Volume 61, Issue 9, Pages 1441-1444Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/civ575
Keywords
severe malaria; artesunate; quinine; Plasmodium falciparum; clinical study
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Funding
- Charite Clinical Scientist Program - Charite Universitatsmedizin Berlin
- Berlin Institute of Health
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Intravenous artesunate improves survival in severe malaria, but clinical trial data from nonendemic countries are scarce. The TropNet severe malaria database was analyzed to compare outcomes of artesunate vs quinine treatment. Artesunate reduced parasite clearance time and duration of intensive care unit and hospital treatment in European patients with imported severe malaria.
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