Journal
CLINICAL INFECTIOUS DISEASES
Volume 61, Issue -, Pages S155-S159Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/civ611
Keywords
tuberculosis; biological markers; biological specimen banks; prospective studies; specimen handling
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Funding
- US Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Department of Health and Human Services
- Indian Department of Biotechnology, the Ministry of Science and Technology
- Indian Council of Medical Research
- US Office of AIDS Research
- US NIAID
- Brazil's Ministry of Health and Department of Science and Technology
- Indonesia National Institute of Health Research and Development
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Progress in tuberculosis clinical research is hampered by a lack of reliable biomarkers that predict progression from latent to active tuberculosis, and subsequent cure, relapse, or failure. Regional Prospective Observational Research in Tuberculosis (RePORT) International represents a consortium of regional cohorts (RePORT India, RePORT Brazil, and RePORT Indonesia) that are linked through the implementation of a Common Protocol for data and specimen collection, and are poised to address this critical research need. Each RePORT network is designed to support local, in-country tuberculosis-specific data and specimen biorepositories, and associated research. Taken together, the expected results include greater global clinical research capacity in high-burden settings, and increased local access to quality data and specimens for members of each network and their domestic and international collaborators. Additional networks are expected to be added, helping to spur tuberculosis treatment and prevention research around the world.
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