4.3 Article

Heart-rate dependent improvement in image quality and diagnostic accuracy of coronary computed tomographic angiography by novel intracycle motion correction algorithm

Journal

CLINICAL IMAGING
Volume 39, Issue 3, Pages 421-426

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.clinimag.2014.11.020

Keywords

Coronary computed tomographic angiography; Motion artifact; Motion correction algorithm; Coronary artery disease

Funding

  1. National Heart, Lung, and Blood Institute of the National Institutes of Health (Bethesda, MD, USA) [R01 HL111141, R01 HL118019, R01HL115150]

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Background: To determine the effect of a novel intracycle motion correction algorithm (MCA) on diagnostic accuracy of coronary computed tomographic angiography. Methods: Coronary artery phantom models were scanned at static and heart rate (HR) simulation of 60-100 beat/min and reconstructed with a conventional algorithm and MCA. Results: Among 144 coronary segments, improvements in image interpretability, quality, and diagnostic accuracy by MCA were observed for HRs of 80 and 100 (P<.05 for all), but not for HR of 60. Conclusion: Novel intracycle MCA demonstrates improved HR-dependent image interpretability, and quality and accuracy, particularly at higher HRs. (C) 2015 Elsevier Inc. All rights reserved.

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