Journal
VIRUS GENES
Volume 53, Issue 1, Pages 21-34Publisher
SPRINGER
DOI: 10.1007/s11262-016-1388-9
Keywords
Poxvirus; Skunkpox; Volepox; Raccoonpox; Orthopox; Evolution; Phylogeny
Categories
Funding
- Natural Sciences and Engineering Research Council
Ask authors/readers for more resources
The complete genomes of a skunkpox, volepox, and raccoonpox virus were sequenced and annotated. Phylogenetic analysis of these genomes indicates that although these viruses are all orthopoxviruses, they form a distinct clade to the other known species. This supports the ancient divergence of the North American orthopoxviruses from other members of the orthopoxviruses. Only two open reading frames appear to be unique to this group of viruses, but a relatively small number of insertions/deletions contribute to the varied gene content of this clade. The availability of these genomes will help determine whether skunkpox and volepox viruses share the characteristics that make raccoonpox a useful vaccine vector.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available