Journal
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Volume 181, Issue -, Pages 10-14Publisher
ELSEVIER
DOI: 10.1016/j.vetimm.2016.02.003
Keywords
Tuberculosis; Cattle; Differential diagnosis; BCG; Vaccination
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Bovine tuberculosis remains a major economic and animal welfare concern worldwide. As part of control strategies, cattle vaccination is being considered. This approach, used alongside conventional control policies, also requires the development of vaccine compatible diagnostic assays to distinguish infected from vaccinated animals (DIVA). In this review we discuss recent advances in DIVA development based on the detection of host cellular immune responses by blood testing or skin testing approaches. Crown Copyright (C) 2016 Published by Elsevier B.V. All rights reserved.
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