Journal
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Volume 53, Issue 6, Pages 879-885Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/cclm-2014-1127
Keywords
biological variation; checklist; critical appraisal; reference values
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Data on biological variation are used for many purposes in laboratory medicine but concern exists over the validity of the data reported in some studies. A critical appraisal checklist has been produced by a working group established by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) to enable standardised assessment of existing and future publications of biological variation data. The checklist identifies key elements to be reported in studies to enable safe accurate and effective transport of biological variation data sets across healthcare systems. The checklist is mapped to the domains of a minimum data set required to enable this process.
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