Journal
TRENDS IN CARDIOVASCULAR MEDICINE
Volume 26, Issue 4, Pages 364-373Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2015.10.004
Keywords
Metabolic syndrome; Diabetes; Dyslipidemia; Hypertension; Nutrition; Obesity
Categories
Funding
- Center for Human Nutrition, UT Southwestern Medical Center, United States
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The metabolic syndrome is a multiplex risk factor for atherosclerotic cardiovascular disease and type 2 diabetes. It is composed of atherogenic dyslipidemia, elevated blood pressure, insulin resistance and elevated glucose, a pro-thrombotic state, and a pro-inflammatory state. Excess energy intake and concomitant obesity are the major drivers of the syndrome. Lifestyle intervention can reverse metabolic risk factors, but at times, drug therapies or bariatric surgery may be required to control more overt risk factors.
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