Journal
TRENDS IN CARDIOVASCULAR MEDICINE
Volume 26, Issue 6, Pages 515-523Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tcm.2016.03.001
Keywords
Cigarette smoking; Electronic cigarettes; Nicotine; Cardiovascular disease
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Funding
- US Public Health Service grants from the National Cancer Institute, and Food and Drug Administration Center for Tobacco Products [P50 CA180890]
- [R25 CA113710]
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The cardiovascular safety of nicotine is an important question in the current debate on the benefits vs. risks of electronic cigarettes and related public health policy. Nicotine exerts pharmacologic effects that could contribute to acute cardiovascular events and accelerated atherogenesis experienced by cigarette smokers. Studies of nicotine medications and smokeless tobacco indicate that the risks of nicotine without tobacco combustion products (cigarette smoke) are low compared to cigarette smoking, but are still of concern in people with cardiovascular disease. Electronic cigarettes deliver nicotine without combustion of tobacco and appear to pose low cardiovascular risk, at least with short-term use, in healthy users. (C) 2016 Elsevier Inc. All rights reserved.
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