Journal
TRANSPLANT INFECTIOUS DISEASE
Volume 18, Issue 5, Pages 785-790Publisher
WILEY-BLACKWELL
DOI: 10.1111/tid.12583
Keywords
brincidofovir; disseminated varicella; acyclovir-resistant
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Brincidofovir (BCV) is a broad-spectrum antiviral agent active in vitro against double-stranded DNA viruses including herpesviruses, adenoviruses, polyomaviruses, and poxviruses. We report successful BCV use in management of disseminated acyclovir- and cidofovir-resistant varicella zoster virus in an immunocompromised hematopoietic stem cell transplant patient with chronic graft-versus-host disease who was intolerant to foscarnet.
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