4.2 Article

Fungal meningitis caused by Lomentospora prolificans after allogeneic hematopoietic stem cell transplantation

Journal

TRANSPLANT INFECTIOUS DISEASE
Volume 18, Issue 4, Pages 601-605

Publisher

WILEY-BLACKWELL
DOI: 10.1111/tid.12563

Keywords

lomentosporiosis; stem cell transplant; meningitis; mold; Lomentospora prolifican; Scedosporium prolificans

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Central nervous system lomentosporiosis is a rare pathological condition in immunocompromised patients. We describe a fatal case of meningitis caused by Lomentospora prolificans (which was previously named Scedosporium prolificans), after an allogeneic hematopoietic stem cell transplantation (allo-HSCT). To our knowledge, no cases of Lomentospora meningitis following allo-HSCT have been reported previously. Particularly in neutropenic patients, it is important to consider L. prolificans when a fungal infection is suspected and antifungal agents are ineffective.

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