Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 82, Issue -, Pages 118-125Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2016.05.019
Keywords
Droplet-based microfluidics; Microdroplets; Droplet-based chemical synthesis; High-throughput assays; Lab-on-a-chip
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The ability to perform laboratory operations on small scales using miniaturized devices provides numerous benefits, including reduced quantities of reagents and waste as well as increased portability and controllability of assays. These operations can involve reaction components in the solution phase and as a result, their miniaturization can be accomplished through microfluidic approaches. One such approach, droplet microfluidics, provides a high-throughput platform for a wide range of assays and approaches in chemistry, biology and nanotechnology. We highlight recent advances in the application of droplet microfluidics in chip-based technologies, such as single-cell analysis tools, small-scale cell cultures, in droplet chemical synthesis, high-throughput drug screening, and nanodevice fabrication. (C) 2016 Elsevier B.V. All rights reserved.
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