Journal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Volume 79, Issue -, Pages 71-79Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2015.10.015
Keywords
Bacterial pathogens; Biosensor; Ligands; Whole-bacteria detection; Label-free
Categories
Funding
- Technology for Health program of the CEA
Ask authors/readers for more resources
With the aim of getting earlier, sensitive and specific information on the presence-or absence - of bacterial pathogens, biosensors are getting an increasing interest for more than two decades. This is partly due to their reduced format, to the possibility to address several questions with a single device and also to the increasing panel of physical approaches that can be exploited for signal transducing. When designing a biosensor, the choice of the ligand motif remains a key element as it drives the efficiency and sensitivity of the assay. In this review, we propose to gather and comment different ligands used for the detection of whole cell bacteria. Because time is a crucial issue when looking for a pathogen, our attention was focused on whole cell assays and label-free methods, which enable the user to skip sampling processing steps and decrease the overall test cost. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available