Journal
TOXIN REVIEWS
Volume 35, Issue 3-4, Pages 121-127Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/15569543.2016.1209523
Keywords
Aflatoxin B1; Aspergillus; contaminated food; immunological outcomes; molds
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Aflatoxin B1 is a toxic and secondary metabolite secreted by some natural molds, such as Aspergillus, and has been associated with severe toxic effects in humans and animals. They contaminate food and feed supplies, and are commonly found in grains and nuts. These toxins are synthesized under suitable physical, chemical and biological conditions. High-temperature stress, moisture stress and insect injury of the product are the most important factors in mold invasion and subsequent toxin production. These toxins have different carcinogenic and cytotoxic properties. The immunological effects of exposure to AFB1 are assessed in the present review.
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