Journal
TOXICON
Volume 111, Issue -, Pages 139-142Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.toxicon.2016.01.053
Keywords
Bioconversion; Masked mycotoxins; Zearalenone; Human cell lines; Hydrolysis
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In the matter of foodborne mycotoxins, beside a number of regulated compounds, regulations are totally missing for phase-II plant metabolites - the toxicological knowledge of which is still in its infancy. Currently, zearalenone-14-glucoside is in the pipeline and its toxicological role is under a glowing scientific debate. In our work it clearly showed high toxicological concerns as it is prone to conversion to well-known toxic compounds (i.e. zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. The need of future risk assessment studies has been pointed out accordingly. (C) 2016 Elsevier Ltd. All rights reserved.
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