Journal
TOXICON
Volume 121, Issue -, Pages 36-40Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.toxicon.2016.08.015
Keywords
Lake Baikal; Benthic cyanobacteria; Tolypothrix distorta; Saxitoxin; Paralytic shellfish toxins; Sponge disease
Categories
Funding
- RFBR grant [16-54-44035]
- [VI.61.1.4]
- [VI.55.1.3]
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Cyanobacteria were screened from the surface of diseased sponges, stone and bedrock in Lake Baikal for the presence of saxitoxin using enzyme-linked immunosorbent assay. In sequel, eight paralytic shellfish toxin (PST) variants were identified using a MALDI mass spectrometry. Microscopic examination found that Tolypothrix distorta dominated in the biofouling samples. PCR and sequencing detected sxtA gene involved in saxitoxin biosynthesis, thereby providing evidence of the PST producing potential of Baikal cyanobacterial communities inhabiting different substrates. (C) 2016 Elsevier Ltd. All rights reserved.
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