Journal
TETRAHEDRON LETTERS
Volume 57, Issue 10, Pages 1158-1160Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.01.108
Keywords
Acetylation; Trimethylsilyl iodide; Microwave assisted synthesis
Categories
Funding
- DST-SERB, New Delhi, India [GPP0299]
- CSIR, New Delhi, India [MLP3000/03, CSC0131]
Ask authors/readers for more resources
A method for N-acetylation of amines has been developed using acetonitrile as an acylating agent and in situ generated trimethylsilyl iodide as the catalyst under microwave heating condition. The reaction is selective toward aromatic amines while aliphatic amines remain intact. The process eliminates the requirement of toxic acylating reagents like acetic anhydride and acetyl chloride. (C) 2016 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available