Journal
TETRAHEDRON LETTERS
Volume 57, Issue 43, Pages 4821-4823Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.09.050
Keywords
Perylene; Nucleosides; Butadiynes; Sonogashira coupling; Fluorescence
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Funding
- Russian Science Foundation [15-15-00053]
- Russian Science Foundation [15-15-00053] Funding Source: Russian Science Foundation
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Two novel analogues of the highly fluorescent and potent antiviral compound, 5-(perylen-3-ylethynyl)-2'-deoxyuridine, containing elongated rigid linkers, butadiyne and 1,4-diethynylphenylene, were synthesized from the corresponding trimethylsilyl alkynes using a one-pot desilylation/Sonogashira reaction as the key step. Their spectral properties are compared to those of the parent perylenylethynyl nucleoside. (C) 2016 Published by Elsevier Ltd.
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