Journal
TETRAHEDRON LETTERS
Volume 57, Issue 44, Pages 4935-4938Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.09.077
Keywords
Vanadium; Molecular oxygen; Quinazolinones; Alcohols; Aldehydes
Categories
Funding
- National Natural Science Foundation of China [21403219]
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An efficient and simple VO(acac)(2)-catalyzed approach to the synthesis of quinazolinones has been developed. Various substituted quinazolinones have been synthesized from 2-aminobenzamides with alcohols or aldehydes in good to excellent yields with molecular oxygen as the oxidant. The process can also be scaled up. (C) 2016 Elsevier Ltd. All rights reserved.
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