4.4 Article

Convenient synthesis of deuterium labelled sesquiterpenes

Journal

TETRAHEDRON LETTERS
Volume 57, Issue 40, Pages 4496-4499

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.08.079

Keywords

Sesquiterpenes; Isotopic labelling; Deuterium; Terpenoids

Funding

  1. New Zealand Ministry of Business, Innovation and Employment, New Zealand
  2. University of Auckland

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Sesquiterpenes are an important class of molecules, with roles ranging from pollination and signalling to defense mechanisms. Despite their apparent importance, the limited number of commercial standards has hindered their study and precise quantification. Herein, we report the syntheses of fourteen labelled sesquiterpenes with a high level of deuterium incorporation (>95%) for applications in MS-based studies. (C) 2016 Elsevier Ltd. All rights reserved.

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