Journal
TETRAHEDRON LETTERS
Volume 57, Issue 9, Pages 1006-1010Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.01.074
Keywords
Multi-component reactions (MCRs); Solvent-free conditions; Pyridazino[1,2-a]indazole-triones; Indazolo[2,1-b]phthalazine-trione; Ionic liquid
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Funding
- Shahid Bahonar University of Kerman Faculty Research committee funds
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A rapid and efficient one-pot, four-component protocol for the synthesis of novel 2H-pyridazino[1,2-a]indazole-1,6,9(11H)-triones (6) and 2H-indazolo[2,1-b]phthalazine-1,6,11-triones (7) has been developed using a stable and reusable Bronsted acidic ionic liquid N,N-diethyl-N-sulfoethanammonium chloride ([Et3N-SO3H]Cl). A range of diverse aldehydes were successfully applied and the corresponding products obtained in good to excellent yields without any by-products. (C) 2016 Elsevier Ltd. All rights reserved.
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