Journal
TETRAHEDRON LETTERS
Volume 57, Issue 49, Pages 5501-5504Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.10.102
Keywords
Copper-catalyzed; Thio-amides; C-S coupling; Arylboronic acids; Biological activity
Categories
Funding
- Russian Science Foundation [14-34-00017]
- Russian Fund of Basic Research [16-33-60166]
- Russian Science Foundation [14-34-00017] Funding Source: Russian Science Foundation
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A convenient and efficient catalytic procedure for the selective S-arylation of 2-thioxoimidazolidin-4-ones to give novel S-aryl substituted 2-thiohydantoins under mild reaction conditions using arylboronic acids is described. The anticancer activity of the compounds were evaluated in vitro. (C) 2016 Elsevier Ltd. All rights reserved.
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