4.4 Article

Structural characterization of dimeric indole alkaloids from Psychotria brachybotrya by NMR spectroscopy and theoretical calculations

Journal

TETRAHEDRON LETTERS
Volume 57, Issue 12, Pages 1331-1334

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.02.040

Keywords

Psychotria brachybotrya; Dimeric tryptamine-related alkaloid; Brachybotryne; Brachybotryne-N-oxide; Conformational analysis

Funding

  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior - Brazil (CAPES)
  2. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico - Brazil (CNPq)

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Chemical study of Psychotria brachybotrya led to the isolation of a new dimeric tryptamine-related alkaloid, named brachybotryne (1), and its N-oxide derivative 2, together with a known compound identified as bufotenine (3). In order to corroborate the NMR experimental data, a conformational analysis and chemical shifts calculation were carried out for compound 1. (C) 2016 Elsevier Ltd. All rights reserved.

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