Journal
TETRAHEDRON
Volume 72, Issue 47, Pages 7599-7605Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2016.10.016
Keywords
Coumarin; Dihydropyrano[2,3-c]pyrazole; Ultrasound irradiation; Multi-component reaction; One-pot synthesis; L-Proline
Categories
Funding
- National Natural Science Foundation of China [21462041]
- Natural Science Foundation for Distinguished Young Scholars of Xinjiang Uyghur Autonomous Region [Qn2015jq002]
- Tianshan Talent Cultivation Project of Xinjiang Uyghur Autonomous Region
Ask authors/readers for more resources
A simple and convenient approach to the synthesis of coumarin-containing dihydropyrano[2,3-c]pyrazoles via four-component reaction of beta-dicarbonyl compound, phenylhydrazine, aromatic aldehydes and malononitrile in EtOH catalyzed by L-proline under ultrasonic irradiation is described. The reaction gives the coumarin-containing dihydropyrano[2,3-c]pyrazoles in good to excellent yields at room temperature. This method provides several advantages, such as shorter reaction time, environmental friendliness, simple workup procedure and higher yields. (C) 2016 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available