4.4 Article

Zinc Chloride Catalyzed, Dipolar Aprotic Solvent-Mediated, One-Pot Synthesis of 2-[(Benzo[d]thiazol-2-ylamino)(phenyl)methyl] phenols

Journal

SYNLETT
Volume 27, Issue 20, Pages 2795-2798

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1588595

Keywords

Betti bases; benzothiazoles; phenols; aldehydes; quinone methides

Funding

  1. SERB-India [SB/FT/LS-297/2012]
  2. UGC-India [41/224/2012 (SR)]
  3. CSIR, India

Ask authors/readers for more resources

A three-component one-pot method has been developed for the synthesis of 2-[( benzo[d]thiazol-2-ylamino)(phenyl) methyl] phenols from a variety of aldehydes, 2-amino-1,3-benzothiazoles, and phenols. Phenol, substituted phenols, and polyhydroxybenzenes participated well, providing the corresponding derivatives in good yields. In the case of polyhydroxybenzenes, for which the formation of positional isomers or dimers might have been possible, the sterically less hindered positional isomer was formed exclusively via the ortho-quinone methide.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available