4.4 Article

Formal Syntheses of 5,8-Disubstituted Indolizidine Alkaloids (-)-205A, (-)-207A, and (-)-235B

Journal

SYNLETT
Volume 28, Issue 4, Pages 481-484

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1588360

Keywords

alkaloid; indolizidine; Evans aldol; Horner-Wadsworth-Emmons olefination; reductive amination

Funding

  1. Council of Scientific and Industrial Research (CSIR)
  2. CSIR, New Delhi [CSC-108]
  3. ORIGIN

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Formal total syntheses of (-)-indolizidines 205A, 207A, and 235B have been accomplished using Evans aldol, Horner-Wadsworth-Emmons olefination and reductive cyclization as key reactions.

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