4.7 Editorial Material

A Dual Base Flipping Mechanism for Archaeal Mismatch Repair

Journal

STRUCTURE
Volume 24, Issue 11, Pages 1859-1861

Publisher

CELL PRESS
DOI: 10.1016/j.str.2016.10.004

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In this issue of Structure, Nakae et al. (2016) report the structure of the archaeal EndoMS endonuclease, which cleaves DNA containing mismatched base pairs. Their data demonstrate a unique dual base flipping mechanism, providing intriguing insights into the molecular evolution of protein machineries involved in DNA mismatch repair.

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