Journal
SENSORS AND ACTUATORS B-CHEMICAL
Volume 236, Issue -, Pages 109-115Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2016.05.144
Keywords
Fluorescence; Ratiometric; FRET; Copper; Cell imaging; Naphthalimide-rhodaminea
Funding
- National Science Foundation of China [21572209]
- International Technology Cooperation Plan of Henan Province of China [152102410018]
- Science-Technology Foundation for Outstanding Young Scientists of Henan Academy of Agricultural Sciences [2016YQ22]
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Based on fluorescent resonance energy transfer (FRET), we developed a ratiometric fluorescent probe 1 for sensing Cu2+. As expected, probe 1 exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Cu2+ in aqueous solution. A significant color change from pale yellow to pink could be observed, enabling naked-eye detection of Cu2+. Furthermore, fluorescence imaging experiment of Cu2+ in living MGC-803 cells demonstrated its value of practical applications in biological systems. (C) 2016 Elsevier B.V. All rights reserved.
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