Journal
SENSORS AND ACTUATORS A-PHYSICAL
Volume 251, Issue -, Pages 84-91Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.sna.2016.09.040
Keywords
Microfluidic mixing; Continuous-flow; Magnetic microbeads; Lab-on-a-chip
Funding
- National Science Foundation [CBET-1159726]
- United States Department of Agriculture [2014-67017-21703]
- NIFA [688486, 2014-67017-21703] Funding Source: Federal RePORTER
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Presented here is a novel method for mixing in a microfluidic channel via an array of rotating magnetic microbeads. The microbeads rotate around circular permalloy (NiFe) features magnetized by a rotating external magnetic field. This system demonstrates rapid mixing in short channel lengths. The effectiveness of this system is quantified by analyzing the degree of mixing of two streams, one with fluorescence and one without. Our, experiments and numerical simulations reveal that beads orbiting at a high velocity as compared to flow down the channel cause the fluid to form circular coronae that stretch across the microchannel leading to fluid mixing. Under these conditions, rotating magnetic microbeads were able to fully mix the streams in a 270 mu m mixing region. (C) 2016 Published by Elsevier B.V.
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