Journal
SCIENCE
Volume 354, Issue 6308, Pages 54-59Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aaf5098
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Funding
- NIH [1R01DK104339-01, 1R01GM113657-01, LM009012, LM010098]
- NSF [BCS-1317217]
- NIH through the Center of Excellence in Environmental Toxicology at the University of Pennsylvania [T32ES019851-02]
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The spread of modern humans across the globe has led to genetic adaptations to diverse local environments. Recent developments in genomic technologies, statistical analyses, and expanded sampled populations have led to improved identification and fine-mapping of genetic variants associated with adaptations to regional living conditions and dietary practices. Ongoing efforts in sequencing genomes of indigenous populations, accompanied by the growing availability of -omics and ancient DNA data, promises a new era in our understanding of recent human evolution and the origins of variable traits and disease risks.
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