Journal
SADHANA-ACADEMY PROCEEDINGS IN ENGINEERING SCIENCES
Volume 41, Issue 1, Pages 55-65Publisher
SPRINGER INDIA
DOI: 10.1007/s12046-015-0451-x
Keywords
Ant colony optimization; Bacillus subtilis; central composite rotatable design; lipopeptide; response surface methodology
Categories
Funding
- DST [SR/WOS-A/ET-20/2009]
Ask authors/readers for more resources
Central composite rotatable design (CCRD) of experiments was used to obtain data for Lipopeptide and Biomass concentrations from fermentation medium containing the following five components: glucose, monosodium glutamate, yeast extract, MgSO(4)a <...7H(2)O, and K2HPO4. Data was used to develop a second order regression response surface model (RSM) which was coupled with ant colony optimization (ACO) to optimize the media compositions so as to enhance the productivity of lipopeptide. The optimized media by ACO was found to yield 1.501 g/L of lipopeptide concentration which was much higher compared to 1.387 g/L predicted by Nelder-Mead optimization (NMO). The optimum from ACO was validated experimentally. RSM-based ACO is thus shown to be an effective tool for medium optimization of biosurfactant production.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available